Anti-4-1BB antibodies and methods of making and using thereof
US11987635B2 · kind B2 · utility
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6Claims
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Key dates
| Filing date | Jun 22, 2018 |
| Grant date | May 21, 2024 |
| Priority date | — |
| Expiry date | Aug 8, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/92
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The application provides anti-4-1BB monoclonal antibodies, antigen binding portions thereof, therapeutic compositions thereof and/or nucleic acid encoding the same, and their use to upregulate the function of T-cells to enhance cell-mediated immune responses in the treatment of cancer and other T-cell dysfunctional disorders.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.