Patent · US Active

RPE cell populations and methods of generating same

US11987810B2 · kind B2 · utility

0Cited by

35References

15Claims

0Family size

Assignee

CELL CURE NEUROSCIENCES LTD. · IL

Inventors

Osnat Bohana-Kashtan · Tel Mond, IL
Lior Ann Rosenberg Belmaker · Shoham, IL
Ofer Wiser · Jerusalem, IL

Key dates

Filing date	Dec 8, 2021
Grant date	May 21, 2024
Priority date	—
Expiry date	Dec 8, 2041

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2533/52
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A population of human polygonal RPE cells is disclosed. At least 95% of the cells thereof co-express premelanosome protein (PMEL17) and cellular retinaldehyde binding protein (CRALBP), wherein the trans-epithelial electrical resistance of the cells is greater than 100 ohms. Methods of generating same are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.