Concentration-dependent self-interaction assay
US11988668B2 · kind B2 · utility
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19Claims
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Key dates
| Filing date | Jul 20, 2022 |
| Grant date | May 21, 2024 |
| Priority date | — |
| Expiry date | Jul 20, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/587
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods for producing high concentration protein formulations having high stability are provided. Assays for selecting proteins and formulation conditions that have high self-repulsive attributes are used as an early step in the manufacturing process. Specifically, a protein concentration-dependent self-interaction nanoparticle spectroscopy method is employed as a protein colloidal interaction assay.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.