Apparatus for collagen evaluation and prognostic prediction of colorectal cancer and storage medium

US11990241B2 · kind B2 · utility

Assignee

• SHENZHEN PEOPLE'S HOSPITAL · CN

Inventors

• Jun Yan · Cincinnati, US
• Shumin Dong · Lo Wu, CN
• Botao Yan · Lo Wu, CN
• Weisheng Chen · Allen, US
• Xiaoyu Dong · Lo Wu, CN
• Xiumin Liu · Ellicott City, US
• Shuhan Zhao · Lo Wu, CN
• Jiaxin Cheng · Lo Wu, CN
• Yanfeng Dong · Shandong, CN
• Wei Jiang · Zhejiang, CN
• Dexin Chen · Nanning, CN
• Guoxin Li · Lo Wu, CN

Key dates

• Filing date: Nov 15, 2022
• Grant date: May 21, 2024
• Expiry date: Nov 15, 2042

Classification

• Technology area (CPC G): Physics
• CPC primary: G06V2201/03
• WIPO field: Computer technology
• WIPO sector: Electrical engineering

Abstract

A computer readable storage medium is provided. When contents of the computer readable storage medium are executed by a processor, multi-photon imaging may be performed on a histopathological section containing tumor environment information, and pathological partitioning of a tumor microenvironment may be further performed through image processing. A value of each collagen feature parameters, such as a morphological feature parameter, an energy feature parameter and a texture feature parameter, may be extracted from a tumor tissue region, an invasive margin (IM) region and a normal tissue (N) region. An inter-region difference and a variation may be calculated according to feature parameters of regions. A collagen feature scoring model may be established. A collagen feature score may be calculated with the collagen feature parameters input to the model.