Micronized eggshell membrane particles and the use thereof to promote the healing of wounds

US11992508B2 · kind B2 · utility

Assignee

• BIOVOTEC AS · NO

Inventors

• Ralf Schmidt · Berlin, DE
• Henri-Pierre Suso · Oslo, NO
• Enda Kenny · Dublin, IE

Key dates

• Filing date: Oct 28, 2015
• Grant date: May 28, 2024
• Expiry date: Oct 28, 2035

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention provides a particle consisting essentially of micronized ESM and having a mean particle diameter of less than 100 μm for use in promoting the healing of a chronic wound at risk of, or in which there is, (i) an inappropriate level of matrix-metalloproteinase (MMP) activity against extracellular matrix (ECM) proteins and/or peptide growth or differentiation factors, and/or (ii) an excessive inflammatory response. The invention further provides pharmaceutical compositions, wound dressings and implantable medical devices comprising the micronized ESM-containing particles for use in said treatments. The invention still further provides methods for manufacturing the micronized ESM-containing particles and the compositions, dressings and implantable medical devices comprising the same.