Therapeutic uses for sodium thiosulfate and formulations
US11992530B2 · kind B2 · utility
1Cited by
20References
26Claims
0Family size
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Inventor
Key dates
| Filing date | Nov 22, 2022 |
| Grant date | May 28, 2024 |
| Priority date | — |
| Expiry date | Nov 22, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC01P2002/72
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein is anhydrous sodium thiosulfate, methods for synthesizing anhydrous sodium thiosulfate, pharmaceutical compositions thereof, and methods of treating ototoxicity. Anhydrous sodium thiosulfate is synthesized from sodium sulfite, sulfur, and cetylpyridinium chloride. The anhydrous sodium thiosulfate is formulated into a pharmaceutical composition comprising a buffer and solvent. These compositions are useful for eliminating or reducing ototoxicity in pediatric patients receiving platinum-based chemotherapeutics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.