Method and device for continuously synthesizing cyclopropane compounds
US11993552B2 · kind B2 · utility
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17Claims
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Key dates
| Filing date | Jul 2, 2019 |
| Grant date | May 28, 2024 |
| Priority date | — |
| Expiry date | Sep 30, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2601/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure discloses a method and a device for continuously synthesizing cyclopropane compounds. The method includes the following steps: continuously performing a synthetic reaction of a diazomethane precursor in a first reactor, the reaction product of the first reactor flowing into a separator for stratification, the organic phase obtained by stratification overflowing into a second reactor, continuously consuming the diazomethane precursor in a second reactor to prepare diazomethane and performing an electron-rich monoolefin cyclopropanation reaction in situ so as to obtain the cyclopropane compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.