Coated flow path components for chromatographic effects
US11994499B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 25, 2020 |
| Grant date | May 28, 2024 |
| Priority date | — |
| Expiry date | Feb 28, 2040 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/567
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present disclosure relates to the determination of analytes in a sample using chromatography. The present disclosure provides methods of separating an analyte from a sample. The method includes introducing a sample comprising the analytes into a chromatographic system. The chromatographic system has a flow path disposed in an interior of the chromatographic system, at least a portion of the flow path having an active coating, and a chromatographic column having a stationary phase material in an interior of the chromatographic column that facilitates separation of the analytes in the sample through interaction with at least one analyte in the sample. The active coating is selected to interact with at least one analyte in the sample through (1) a repulsive force, (2) a secondary interaction, or (3) a retention mechanism distinct from the interaction with the stationary phase material.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.