Compositions and methods for treating drug-tolerant glioblastoma
US11998540B2 · kind B2 · utility
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Key dates
| Filing date | Mar 24, 2016 |
| Grant date | Jun 4, 2024 |
| Priority date | — |
| Expiry date | Mar 24, 2036 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K2300/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides compositions and methods for the treatment of drug-tolerant glioblastoma, and in particular glioblastoma stem cells. Specifically, the methods comprise contacting a glioblastoma stem cell with a platelet-derived growth factor receptor alpha inhibitor and one or more of a histone lysine demethylase inhibitor and a Notch inhibitor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.