Patent · US Active

Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors

US11998545B2 · kind B2 · utility

0Cited by
79References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 27, 2023
Grant dateJun 4, 2024
Priority date
Expiry dateJun 27, 2043

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D519/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Provided herein are compounds of the Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which A, B, X1, X2, X3, X4, Ring D, and E have the meanings given in the specification, which are inhibitors of RET kinase and are useful in the treatment and prevention of diseases which can be treated with a RET kinase inhibitor, including RET-associated diseases and disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.