Conjugates and methods of using the same

US11998610B2 · kind B2 · utility

Assignee

• Flagship Pioneering Innovations VI, LLC · US

Inventors

• Spencer Cory PECK · Watertown, US
• Steven John Taylor · Winchester, US
• Elijah Lane BOGART · Cambridge, US
• Devin Forest Reed DOUD · Arlington, US
• Joo Hyun IM · Somerville, US
• Dervla Tamara ISAAC · Boston, US
• Jenny LIU · Cambridge, US
• Ferdinand Edward MASSARI · Beverly, US
• Robert Walter MYERS · Cresskill, US
• John Proudfoot · Newtown, US
• Cheri ROSS · Winthrop, US
• John Patrick CASEY, JR. · Boston, US
• David Arthur Berry · Brookline, US

Key dates

• Filing date: Feb 11, 2021
• Grant date: Jun 4, 2024
• Expiry date: Feb 11, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K7/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Disclosed are conjugates including a recognition element covalently bonded to or linked through a linker to a payload. The payload is a pharmaceutical agent (e.g., an antineoplastic agent, anti-infective agent, or anti-inflammatory agent) or a diagnostic agent. Also disclosed are methods of using the conjugates.