Peptide inhibitors of CRISPR-Cas9
US11999805B1 · kind B1 · utility
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18Claims
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Key dates
| Filing date | May 6, 2020 |
| Grant date | Jun 4, 2024 |
| Priority date | — |
| Expiry date | Sep 7, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y301/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Specific and broad-spectrum inhibitory peptides to CRISPR Cas9 variants (SpyCas9, SauCas9, and CjeCas9) are disclosed. A method of making and using these peptides with therapeutic CRISPR Cas9 (to improve desired targeting) or against harmful CRISPR Cas9 components (already active in a patient) is also disclosed. The peptides combined with a delivery system is also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.