Cancer vaccines for colorectal cancer
US12005104B2 · kind B2 · utility
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9Claims
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Inventor
Key dates
| Filing date | Jul 25, 2019 |
| Grant date | Jun 11, 2024 |
| Priority date | — |
| Expiry date | Mar 10, 2041 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to the field of cancer, in particular colorectal cancer. In particular, it relates to the field of immune system directed approaches for tumor reduction and control. Some aspects of the invention relate to vaccines, vaccinations and other means of stimulating an antigen specific immune response against a tumor in individuals. Such vaccines comprise neoantigens resulting from frameshift mutations that bring out-of-frame sequences of the APC, ARID1A, KMT2D, RNF43, SOX9, TCF7L2, TP53, and ZFP36L2 genes in-frame. Such vaccines are also useful for ‘off the shelf’ use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.