Patent · US Active

Near infrared small molecule probes for the detection of cellular senescence

US12005128B1 · kind B1 · utility

0Cited by

0References

3Claims

0Family size

Assignee

UNM RAINFOREST INNOVATIONS · US

Inventors

Lina Cui · Gainesville, US
Jun Liu · Gainesville, US
Xiaowei Ma · Lo Wu, CN
Ying Wang · Albuquerque, US
Philip Deenik · Albuquerque, US

Key dates

Filing date	Apr 2, 2020
Grant date	Jun 11, 2024
Priority date	—
Expiry date	Jan 6, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG01N2458/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

A probe comprising a biomarker-triggered moiety, a near infrared (NIR) fluorophore reporter, a self-immolative linker and a self-immobilizing moiety for visualization of senescent cells and methods of use thereof.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.