Two-dimensional fluid separation with push-pull modulation
US12005376B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Sep 17, 2019 |
| Grant date | Jun 11, 2024 |
| Priority date | — |
| Expiry date | Jun 4, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2030/326
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A sample separation apparatus includes a first-dimension separation unit for separating the fluidic sample, having a first-dimension outlet for outputting the fluidic sample or fractions thereof, and a second-dimension separation unit for further separating the fluidic sample or fractions thereof. The second-dimension separation unit has a second-dimension inlet fluidically coupled to the first-dimension outlet. A modulation unit, coupled between the first-dimension outlet and the second-dimension inlet at a first coupling point, is configured for withdrawing fluid from the first coupling point and for ejecting fluid into the first coupling point. A second-dimension fluid drive is coupled to a second coupling point located between the first-dimension outlet and the second-dimension inlet and downstream from the first coupling point. The second-dimension fluid drive is configured for generating a fluid flow for driving at least part of the fluidic sample after treatment by the first-dimension separation unit through the second-dimension separation unit.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.