Method for producing CD8alpha+beta+ cytotoxic t cells
US12006512B2 · kind B2 · utility
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15Claims
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Key dates
| Filing date | Jan 19, 2018 |
| Grant date | Jun 11, 2024 |
| Priority date | — |
| Expiry date | Jun 19, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16334
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method efficiently produces cytotoxic T lymphocytes having intrinsic properties of lymphocytes of the acquired immune system suitable for cellular immunotherapy. The method includes culturing CD4/CD8 double-positive T cells in a medium containing IL-7 and a T-cell receptor activator, to induce CD8α+β+ cytotoxic T lymphocytes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.