Methods and systems for rapid detection of microorganisms using infectious agents
US12006531B2 · kind B2 · utility
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17References
11Claims
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Key dates
| Filing date | Nov 5, 2019 |
| Grant date | Jun 11, 2024 |
| Priority date | — |
| Expiry date | Nov 5, 2039 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2795/10243
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed herein are methods and systems for rapid detection of microorganisms in a sample, without culturing for enrichment of the microorganism. A modified bacteriophage is also disclosed which comprises a non-native indicator gene in the late gene region. The indicator product is not a fusion protein. The specificity of infectious agents allows a specific microorganism to be targeted, and an indicator signal may be amplified to optimize assay sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.