Population-specific prediction of prostate cancer recurrence based on stromal morphology features
US12008747B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | May 29, 2020 |
| Grant date | Jun 11, 2024 |
| Priority date | — |
| Expiry date | Sep 10, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06T2207/30081
- WIPO fieldComputer technology
- WIPO sectorElectrical engineering
Abstract
Embodiments discussed herein facilitate determination of one of a probability of prostate cancer recurrence-free survival or a risk factor associated with prostate cancer based on intra-tumor stromal morphology. Example embodiments can perform operations comprising: accessing a digitized histological image of a prostate of a patient, wherein the histological image comprises a region of interest associated with prostate cancer; identifying nuclei of intra-tumoral stromal cells within the region of interest; extracting, for the region of interest of the digitized histological image, one or more features describing the structure of the intra-tumoral stromal cells; and generating, via a model based at least on the one or more features, one of a probability of prostate cancer recurrence-free survival or a risk score associated with prostate cancer for the patient based at least on the extracted one or more features.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.