Chlorin derivatives or pharmaceutically acceptable salts thereof, preparation method and use thereof, and combination thereof with an ultrasonic medical system
US12011482B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 17, 2021 |
| Grant date | Jun 18, 2024 |
| Priority date | — |
| Expiry date | Aug 17, 2041 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N2007/0091
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present disclosure relates to a chlorin derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, an anti-tumor composition including the chlorin derivative or the pharmaceutically acceptable salt thereof, use of the chlorin derivative or the pharmaceutically acceptable salt thereof in the treatment of a tumor, and a combination of the chlorin derivative or the pharmaceutically acceptable salt thereof and an ultrasound medical system. The chlorin derivative or the pharmaceutically acceptable salt thereof has a structure represented by formula (I), and the ultrasonic medical system comprises a transducer ultrasonic bed and a contact agent. The chlorin derivative of the present disclosure can be used in photodynamic therapy and sonodynamic therapy, thereby effectively inhibiting and treating cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.