Method and device for examining the neurovascular coupling at the eye of a patient

US12016630B2 · kind B2 · utility

Assignee

• IMEDOS SYSTEMS GMBH · DE

Inventors

• Walthard Vilser · Rudolstadt, DE
• Martin Skorsetz · Jena, DE
• Thomas Riemer · Jena, DE

Key dates

• Filing date: Mar 29, 2019
• Grant date: Jun 25, 2024
• Expiry date: Sep 22, 2041

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61B3/1241
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

A method and a device for examining the neurovascular coupling at the eye (A) of a patient, wherein an imaging method is used to record an image sequence of images of the fundus of the eye (A), preferably over a baseline phase (BP), a stimulation phase (SP) in which the fundus is stimulated with a flickering light, and a posterior phase (NP). Signals, in particular an averaged quotient signal (Q(t)) representing a vessel response of the vessels of the capillary vessel region to the stimulation, are derived from the image sequence for at least one capillary vessel region of the fundus. The absolute or percentage maximum change (Qmax) of the averaged quotient signal (Q(t)) is then used as an evaluation criterion for the neurovascular coupling.