Primary T-cell expansion
US12016883B2 · kind B2 · utility
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9Claims
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Key dates
| Filing date | Sep 25, 2020 |
| Grant date | Jun 25, 2024 |
| Priority date | — |
| Expiry date | Jul 23, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2501/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are methods of in-vitro primary T cell growth that enrich T cells in a blood sample, stimulate the T cells with anti-CD2, anti-CD3, and/or anti-CD28 and that expand the T cells with a cytokine. Also provided are methods of treating a tumor in a patient using the expanded T cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.