Microparticles containing leuprolide and method for producing the same
US12016897B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jun 3, 2022 |
| Grant date | Jun 25, 2024 |
| Priority date | — |
| Expiry date | Sep 26, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1694
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides microparticles containing leuprolide and a method for producing the same. When the microparticles are administered by injection, they may lower pain due to their small size, control the release rate of leuprolide at a target site, prevent excessive release of leuprolide at an initial stage, enable exposure to a sufficient amount of the drug to exhibit the effect of leuprolide, and exhibit the effect of leuprolide for 1 month or more. The present invention also provides a method for producing microparticles, in which the microparticles have a uniform particle size and a smooth surface and may exhibit the effect of releasing leuprolide sustainably over a long period of time.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.