Patent · US Active

Pregabalin lactam methylene dimer and preparation method therefor

US12018018B2 · kind B2 · utility

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Key dates

Filing dateNov 6, 2018
Grant dateJun 25, 2024
Priority date
Expiry dateAug 10, 2040

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D403/06
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Provided are a pregabalin lactam methylene dimer and a preparation method therefor. The method comprises the following steps: dissolving pregabalin in a reaction solvent, reacting same with an aldehyde in an acidic system and isolating the obtained target product pregabalin lactam methylene dimer. The preparation method for pregabalin lactam methylene dimer provided by the present application has a simple operation, a high product yield, a good purity and a low cost.

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