High throughput oil-emulsion synthesis of bowtie barcodes for paired mRNA capture and sequencing from individual cells
US12018317B2 · kind B2 · utility
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Key dates
| Filing date | Dec 9, 2021 |
| Grant date | Jun 25, 2024 |
| Priority date | — |
| Expiry date | Apr 27, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6869
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for incorporation of unique bowtie-barcodes into a nucleic acid origami nanostructure (FIG. 1). In particular, provided herein are methods that facilitate pairing and analysis of nucleic acids from individual cells using, for example, high-throughput next-generation sequencing.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.