Patent · US Active

Means and methods for single molecule peptide sequencing

US12019076B2 · kind B2 · utility

1Cited by

62References

14Claims

0Family size

Assignees

VIB VZW · BE
UNIVERSITEIT GENT · BE

Inventors

Nico Callewaert · Nevele, BE
Sven Eyckerman · Nazareth, BE
Simon Devos · Sint-Michiels, BE

Key dates

Filing date	Aug 5, 2022
Grant date	Jun 25, 2024
Priority date	—
Expiry date	Aug 5, 2042

Classification

Technology area (CPC G)Physics
CPC primaryG01N33/6824
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

The present invention relates to the field of biochemistry, more particularly to proteomics, more particularly to protein sequencing, even more particularly to single molecule peptide sequencing. The invention discloses methods for single molecule protein sequencing and/or amino acid identification using cleavage inducing agents which are not specific for one particular amino acid, cleave polypeptides step by step from the N-terminus onwards and provide information on the identity of the cleaved amino acids based on the kinetics.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.