Patent · US Active

Methods and compounds for improved immune cell therapy

US12023353B2 · kind B2 · utility

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10Claims

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Assignee

CHEMOTHERAPEUTISCHES FORSCHUNGSINSTITUT GEORG-SPEYER-HAUS · DE

Inventors

Winfried Wels · Emmendingen, DE
Anja Waldmann · Offenbach, DE
Congcong Zhang · Frankfurt, DE
Manuel Kaulich · Frankfurt am Main, DE

Key dates

Filing date	Oct 18, 2018
Grant date	Jul 2, 2024
Priority date	—
Expiry date	Oct 26, 2040

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12N2501/2315
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention pertains to methods and compounds useful in a therapy involving the administration of immune cells to a patient. The method of the invention involves the modification of cells of the immune system with agonists or antagonists of immune regulators such as Interleukin-10 (IL-10) or IL-6, in order to enhance and improve the immunological potential of the immune cells for therapy. Cells modified according to the method of the invention can be administered to a patient to support a treatment of proliferative diseases such as cancer or autoimmune disorders.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.