High-flux ultra-sensitive detection dot array enhancement chip

US12024463B2 · kind B2 · utility

Assignee

• Jiangnan University · CN

Inventors

• Fuwei Pi · Wuxi, CN
• Ling Liu · Glastonbury, US
• Ying Li · Wuxi, CN
• Yuanyuan Zhang · Beijing, CN
• Ziye Yin · Wuxi, CN
• Yuliang Cheng · Saitama, JP
• Lin Lin · Beijing, CN
• Xiulan Sun · Wuxi, CN

Key dates

• Filing date: Oct 9, 2020
• Grant date: Jul 2, 2024
• Expiry date: May 4, 2043

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C03C2218/355
• WIPO field: Measurement
• WIPO sector: Instruments

Abstract

The disclosure discloses a high-flux and ultra-sensitive detection dot array enhancement chip, and belongs to the field of food safety detection. In the disclosure, single-layer Au nano-particles are chemically bonded onto a hydrophilic substrate, an Au nano-material is naturally deposited in holes of the chip under an electrostatic adsorption action, and a regular dot array is formed. Au particles distributed in the holes are separated with a particle surfactant (CTAB) to form plasma gaps so as to enhance the self-assemble of Au nano-particles distributed on hot-spots for a long range effect, thereby improving the sensing signal in detection efficiency and sensitivity of the chip.