Processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)-pyrrolidin-2-yl]imidazo[1,5-a]-pyrazin-1-yl}N-(pyridin-2-yl)-benzamide
US12024520B2 · kind B2 · utility
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3References
29Claims
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Assignee
Inventors
- Paul Allen Bethel
- Lai Chun CHAN
- Katie Grace COOPER
- Robert John COX
- Michael David Golden
- Shaun Alan HUGHES
- Lucinda Victoria Jackson
- Kirsty Jane MILLARD
- Andrew J. Phillips
- Alexander Telford
- Jerry Evarts
- Michael Joseph Lawler
- Remy E. J. N. LITJENS
- Peter Johannes Servaas Savio VAN EIJK
- Mathilda Maria Henrica VERSTAPPEN
- Frank L. M. VOS
- Eric Jurriën ZIJP
- Qiu JUNYING
- Rustam Ferdinand GARREY
- David Allen SHORT
- Angang Wang
Key dates
| Filing date | Aug 28, 2019 |
| Grant date | Jul 2, 2024 |
| Priority date | — |
| Expiry date | Jun 8, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07B2200/13
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present disclosure relates, in general, to improved processes for the preparation of 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)-benzamide, particularly large-scale processes for manufacturing 4-{8-amino-3-[(2S)-1-(but-2-ynoyl)pyrrolidin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-(pyridin-2-yl)benzamide and intermediates used in such processes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.