Anti-Staphylococcus antibodies and uses thereof
US12024556B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 20, 2019 |
| Grant date | Jul 2, 2024 |
| Priority date | — |
| Expiry date | Feb 7, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/94
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Speciated antibodies or antigen-binding fragments that bind staphylococcal antigens are provided, where the antibodies and antigen-binding fragments have attenuated Fc binding to Protein A or homologous protein. Compositions comprising the antibodies and methods of use are also provided. The antibodies and compositions are useful for treating staphylococcal infection, reducing serum or kidney bacterial titers, and treating symptoms associated with staphylococcal infection. The antibodies may also prevent the severity and/or duration of the primary disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.