Modified oligonucleotides targeting SNPs
US12024706B2 · kind B2 · utility
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Key dates
| Filing date | Aug 7, 2020 |
| Grant date | Jul 2, 2024 |
| Priority date | — |
| Expiry date | Aug 7, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2320/53
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel oligonucleotides that enhance silencing of the expression of a gene containing a single nucleotide polymorphism (SNP) relative to the expression of the corresponding wild-type gene are provided. Methods of using novel oligonucleotides that enhance silencing of the expression of a gene containing a SNP relative to the expression of the corresponding wild-type gene are provided.
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