Patent · US Active

Polypeptide having cephalosporin C acylase activity and use thereof

US12024729B2 · kind B2 · utility

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18Claims
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Assignee

Inventors

Key dates

Filing dateNov 17, 2022
Grant dateJul 2, 2024
Priority date
Expiry dateNov 17, 2042

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y305/01093
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Disclosed herein are a polypeptide having cephalosporin C(CPC) acylase activity and a use thereof. More specifically, a mutant CPC acylase comprising a point mutation introduced thereinto, thereby exhibiting improved enzymatic activity and/or stability, and a use of the mutant CPC acylase for producing 7-aminocephalosporanic acid (7-ACA), are provided.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.