Process for production of essentially pure delta-9-tetrahydrocannabinol
US12029718B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 2021 |
| Grant date | Jul 9, 2024 |
| Priority date | — |
| Expiry date | Nov 9, 2041 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/08
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
The present invention describes a method which outlines a process for conversion of CBD to a Δ9-tetrahydrocannabinol (Δ9-THC) compound or derivative thereof involving treating a naturally produced CBD intermediate compound with an organoaluminum-based Lewis acid catalyst, under conditions effective to produce the Δ9-tetrahydrocannabinol compound or derivative thereof at a relatively high concentration. The source of the CBD is from industrial hemp having less than 0.3% Δ9-THC and extracting and purifying a CBD distillate or isolate or a combination thereof. This procedure will produce Δ9-THC that is essentially free from any other cannabinoids other than some trace amounts of the initial CBD starting material, or about 95% Δ9-THC and 2-4% CBD. Another aspect of the present invention relates to a process for further purification and enrichment of the Δ9-THC using distillation and collecting an essentially pure fraction of Δ9-THC using additional distillation or enrichment form of purification. Included are methods and processes to scale the reaction from the lab to large scale manufacturing. Included are methods for adding a molecule marker to authenticate high purity Δ9-THC product…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.