Base editing of PCSK9 and methods of using same for treatment of disease
US12029795B2 · kind B2 · utility
0Cited by
6References
24Claims
0Family size
Assignee
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Key dates
| Filing date | Apr 9, 2021 |
| Grant date | Jul 9, 2024 |
| Priority date | — |
| Expiry date | Apr 20, 2041 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/80
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided herein are compositions for gene modification or editing and methods of using same to treat or prevent certain conditions. Specific compositions and methods capable of safely and effectively editing gene targets expressed in the liver to durably lower LDL-C thereby treating a leading cause of cardiovascular disease are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.