Methods and compositions for modulating a genome
US12031129B2 · kind B2 · utility
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3References
16Claims
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Key dates
| Filing date | Dec 6, 2019 |
| Grant date | Jul 9, 2024 |
| Priority date | — |
| Expiry date | Feb 10, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods and compositions for modulating a target genome are disclosed. The composition may comprise a first RNA encoding a polypeptide comprising a retrotransposase reverse transcriptase domain and a retrotransposase endonuclease domain. The composition may also comprise a second RNA comprising a sequence that binds the polypeptide and a heterologous object sequence. The composition may insert the sequence of the heterologous object sequence into a target DNA.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.