Therapeutic treatment of skin disease with recombinant commensal skin microorganisms
US12036248B2 · kind B2 · utility
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5Claims
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Key dates
| Filing date | Jun 2, 2020 |
| Grant date | Jul 16, 2024 |
| Priority date | — |
| Expiry date | Jun 2, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/10
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to methods for treating or preventing abnormal skin conditions in a human in need thereof, comprising administering a cell culture composition comprising a living culture of bacteria comprising at least one engineered strain that produces a recombinant polypeptide for therapeutic treatment of the abnormal skin condition. The invention also relates to pharmaceutical compositions containing, as the active principle, engineered microorganisms expressing non-vaccinogenic pharmacologically active recombinant therapeutic polypeptides in order to treat or prevent abnormal skin conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.