Strain for preventing and treating metabolic diseases and use thereof

US12036251B2 · kind B2 · utility

Assignees

• SPH SINE PHARMACEUTICAL LABORATORIES CO., LTD · CN
• SHANGHAI INSTITUTE OF ENDOCRINE AND METABOLIC DISEASES · CN

Inventors

• Bin WEN · Shanghai, CN
• Guang NING · Shanghai, CN
• Xin Ma · Bethany, US
• Weiqing WANG · Shanghai, CN
• Hongjing YU · Shanghai, CN
• Jie Hong · Jing County, CN
• Ningyun SUN · Shanghai, CN
• Jiqiu Wang · Shanghai, CN
• Peijun Yin · Shanghai, CN
• Ruixin LIU · Shanghai, CN
• Yuan Gao · San Diego, US
• Shasha Wang · Shanghai, CN

Key dates

• Filing date: Sep 25, 2019
• Grant date: Jul 16, 2024
• Expiry date: Mar 17, 2041

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12R2001/01
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Provided are an Akkermansia muciniphila strain and use thereof in preventing and treating metabolic diseases. This strain is named Akkermansia muciniphila SSYD-3 and the accession number thereof is CGMCC No. 14764. This strain is more ideal than the existing Akkermansia strain ATCC BAA835 in respect of fermentation performance, storage stability, acid and bile resistance, and the effect on treating metabolic diseases.