Polyvalent sting activating compositions and uses thereof
US12036319B2 · kind B2 · utility
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4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 8, 2021 |
| Grant date | Jul 16, 2024 |
| Priority date | — |
| Expiry date | Mar 5, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F2438/01
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Described herein are therapeutic pH responsive compositions useful for the treatment of cancer. The compositions involve combining a STING activating polymer micelle, such as PC7A, with a non-peptide STING agonist, such as cGAMP. Methods of administering these compositions in the treatment of cancer are also disclosed. These methods include administration of the pharmaceutical compositions by intratumoral injection in the treatment of solid tumors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.