Inverse agonistic anti-US28 antibodies
US12037382B2 · kind B2 · utility
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22Claims
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Key dates
| Filing date | Feb 5, 2019 |
| Grant date | Jul 16, 2024 |
| Priority date | — |
| Expiry date | Nov 5, 2041 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/045
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a novel class of antagonistic and inverse agonistic anti-US28 antibodies, more specifically to single heavy chain variable domain antibodies (VHH) and variants and modifications thereof. The invention further relates to methods for producing these antibodies and to the use of the antibodies in methods for diagnostic and therapeutic purposes, especially for treatment of an individual suffering from a CMV-positive tumor such as glioblastoma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.