Patent · US Active

Method for obtaining dissectates microscopic sample, laser microdissection system and computer program

US12038357B2 · kind B2 · utility

0Cited by

2References

16Claims

0Family size

Assignee

LEICA MICROSYSTEMS CMS GMBH · DE

Inventors

Falk Schlaudraff · Hausen, DE
Florian Hoffmann · Ladenburg, DE
Christoph Greb · Marburg, DE

Key dates

Filing date	Feb 9, 2022
Grant date	Jul 16, 2024
Priority date	—
Expiry date	Jan 19, 2043

Classification

Technology area (CPC G)Physics
CPC primaryG02B21/36
WIPO fieldMeasurement
WIPO sectorInstruments

Abstract

A method for obtaining dissectates from a microscopic sample using a laser microdissection system having a laser unit includes: a) at least partially circumcising and releasing from the sample dissectate regions of the sample as the dissectates using laser pulses provided by the laser unit; b) transferring the dissectates, by being released from the sample, along dissectate trajectories into receptacles of a dissectate collection unit; and c) positioning the receptacles of a dissectate collection unit using a positioning unit to collect the dissectates. The positioning of the receptacles of the dissectate collection unit using the positioning unit is automatically performed based on estimates of the dissectate trajectories, the estimates of the dissectate trajectories being obtained in a learning mode, the learning mode including obtaining dissectates by repeatedly performing at least steps a) and b). Parameters of the dissectate trajectories are determined for a plurality of dissectates.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.