Methods and compositions for promoting the structural integrity of scaffolds for tissue engineering

US12042369B2 · kind B2 · utility

Assignee

• Harvard Apparatus Regenerative Technology, Inc. · US

Inventors

• Ron Sostek · Newton, US
• David Green · Dover, US
• Linghui Meng · Framingham, US
• Sherif Soliman · Holliston, US
• Joseph Consiglio · Ashland, US

Key dates

• Filing date: Sep 9, 2019
• Grant date: Jul 23, 2024
• Expiry date: Sep 9, 2039

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61F2250/0082
• WIPO field: Medical technology
• WIPO sector: Instruments

Abstract

Aspects of the disclosure relate to synthetic tissue or organ scaffolds and methods and compositions for promoting or maintaining their structural integrity. Aspects of the disclosure are useful to prevent scaffold damage (e.g., delamination) during or after implantation into a host. Aspects of the disclosure are useful to stabilize tissue or organ scaffolds that include electrospun fibers.