Injectable fosaprepitant composition
US12042504B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Jul 19, 2021 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Jan 7, 2042 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/40
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present application and its embodiments teach stable compositions of fosaprepitant or a pharmaceutically acceptable salt thereof with such compositions lacking polysorbate 80 and containing dual functional excipients of hydrolysis inhibition and solubility enhancement. Further described are methods of preparation of such compositions. Among other advantages of contemplated compositions, fosaprepitant hydrolysis degradation is kept low and the compositions maintain physically and chemically stable for prolonged period.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.