Prekallikrein-modulating compositions and methods of use thereof
US12042509B2 · kind B2 · utility
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36Claims
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Key dates
| Filing date | Sep 30, 2022 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Sep 30, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21034
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Aspects of the disclosure provide compounds, compositions, and methods for modulating the expression or activity of plasma prekallikrein (PKK). In some aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of PKK mRNA in a cell or animal. In some aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of PKK protein in a cell or animal.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.