Killer cell capable of efficiently and stably expressing antibody, and uses thereof
US12042515B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Jun 19, 2017 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Dec 14, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2800/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Provided is a transgenic killer cell, the genome of which is stably integrated with a coding sequence comprising an antibody of a human Fc section, or an expression cassette of a coding sequence comprising a chimeric antigen receptor or an inhibitory or agonistic antibody, and an inverted terminal repeat sequence from a transposon at both ends. Also provided is a pharmaceutical composition comprising the transgenic killer cell, and uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.