Methods of reducing particle formation and compositions formed thereby
US12042538B2 · kind B2 · utility
0Cited by
116References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 10, 2018 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Apr 11, 2039 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0019
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Biopharmaceutical compositions and drug products disclosed herein exhibit reduced amounts of subvisible particle formation. Compositions and drug products disclosed herein comprise a protein and a surfactant or stabilizer including high percentage amounts (e.g., at least 97%) of a long-chain fatty acid ester. Also disclosed herein are methods of preparing and storing such compositions and drug products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.