Cell capture and expansion
US12043823B2 · kind B2 · utility
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554References
26Claims
0Family size
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Key dates
| Filing date | Mar 23, 2022 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Mar 23, 2042 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/52
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Implementations are described that relate to methods and systems for growing cells in a hollow fiber bioreactor. In implementations, the cells may be exposed to a number of growth factors including a combination of recombinant growth factors. In other implementations, the cells may be grown in co-culture with other cells, e.g., hMSC's. In implementations, the cells may include CD34+ cells. A coated membrane includes a membrane having a first coating configured to promote cellular adhesion to the membrane and a second coating that includes a soluble protein moiety.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.