Illumination for fluorescence imaging using objective lens
US12044624B2 · kind B2 · utility
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14References
20Claims
0Family size
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Key dates
| Filing date | May 16, 2022 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Oct 14, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG02B6/124
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A system includes: an objective lens; a first light source to feed first illuminating light through the objective lens and into a flowcell (e.g., with a relatively thin film waveguide) to be installed in the system, the first illuminating light to be fed using a first grating on the flowcell; and a first image sensor to capture imaging light using the objective lens, wherein the first grating is positioned outside a field of view of the first image sensor. Dual-surface imaging can be performed. Flowcells with multiple swaths bounded by gratings can be used. An auto-alignment process can be performed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.