Predicting cellular pluripotency using contrast images
US12045982B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Aug 11, 2023 |
| Grant date | Jul 23, 2024 |
| Priority date | — |
| Expiry date | Aug 11, 2043 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG06V2201/04
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Embodiments of the disclosure include methods for implementing a predictive model that predicts pluripotency of cells through a cost efficient and non-destructive means. The predictive model analyzes contrast images captured from the cells and outputs predictions of cellular pluripotency at the cellular level. Thus, implementation of the predictive model guides the selection and isolation of cells that are predicted to be pluripotent. Furthermore, the predictive model facilitates retrospective analyses to correlate pluripotency metrics with differentiation success and further enables tracking of cellular pluripotency over time (e.g., to evaluate differentiation of cells).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.