Analyte sensors employing multiple enzymes and methods associated therewith
US12048539B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Jan 28, 2020 |
| Grant date | Jul 30, 2024 |
| Priority date | — |
| Expiry date | Jan 23, 2042 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/908
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Multiple enzymes may be present in the active area(s) of an electrochemical sensor to facilitate analysis of one or more analytes. The multiple enzymes may function independently to detect several analytes or in concert to detect a single analyte. One sensor configuration includes a first active area and a second active area, where the first active area has an oxidation-reduction potential that is sufficiently separated from the oxidation-reduction potential of the second active area to allow independent signal production. Some sensor configurations may have an active area overcoated with a multi-component membrane containing two or more different membrane polymers. Sensor configurations having multiple enzymes capable of interacting in concert include those in which a first enzyme converts an analyte into a first product and a second enzyme converts the first product into a second product, thereby generating a signal at a working electrode that is proportional to the analyte concentration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.