Compositions and methods for activating NRF2-dependent gene expression
US12048686B2 · kind B2 · utility
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Key dates
| Filing date | Oct 14, 2019 |
| Grant date | Jul 30, 2024 |
| Priority date | — |
| Expiry date | Oct 25, 2040 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/14
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Embodiments are directed to a series of novel small molecule activators of NRF2 dependent gene expression that are evaluated in an effort to develop therapeutic methods against diseases with deregulated KEAP1-NRF2 signaling.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.