Spirocyclic degronimers for target protein degradation
US12048748B2 · kind B2 · utility
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21Claims
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Key dates
| Filing date | Nov 11, 2021 |
| Grant date | Jul 30, 2024 |
| Priority date | — |
| Expiry date | Apr 24, 2042 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides compounds that have spirocyclic E3 Ubiquitin Ligase targeting moieties (Degrons), which can be used as is or linked to a targeting ligand for a protein that has been selected for in vivo degradation, and methods of use and compositions thereof as well as methods for their preparation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.